The second key factor is the increasing development of sustained/controlled release formulations. Biosimilars have also entered the market, creating a highly competitive landscape. Monoclonal antibodies (mAbs) are expected to reach combined global sales of US$150 billion (£134 billion) by 2022. The first one is the significant growth of biologics. This new paradigm could be attributed to several key factors. High-viscosity formulations have become increasingly prevalent over the last few years in the pharmaceutical industry. Safety – non-contact, non-invasive and needle-free deliveryĪtomisation of Highly Viscous Formulations.Overdose-free and high surface coverage – precise delivery of a small dose to a large surface area – increasing the drug’s bioavailability.Delivery in any patient posture, in particular, in any patient’s head position for intranasal, buccal or auricular administration.Indeed, spray- or mist-based delivery presents many advantages over conventional methods: Over many years, a variety of spray devices have been developed, such as nasal or buccal sprays, inhalation systems and even spray-on bandage devices. This is an advantage when rapid drug absorption and onset of action are desired.ĭepending on the route of administration, the formulation and the dosage, a delivery device may be needed to properly administer the drug. Compared with the conventional oral and parenteral routes, it is claimed that topical administration offers the advantages of being non-invasive and avoiding first-pass metabolism in the liver by enabling the drug to enter directly into the circulatory system. The choice of delivery route for a drug depends not only on the site of desired action, but also on its properties – its absorption by the body and the environment in which it will be administered. There is a huge need to overcome high-viscosity formulation challenges with specific spray devices.” “As the biologic and controlled-release formulation markets grow, However, drugs can also be delivered via other routes, such as the enteral route through tubing in the gastro-intestinal tract, inhalation to the lungs via the mouth or even the topical route via the skin (cutaneous, transdermal) or a mucosa (intranasal, buccal, auricular, ophthalmic, etc). When one thinks of drug administration, one usually thinks of swallowing pills (oral administration) or getting an injection (parenteral administration). Over the past decades, drug delivery has evolved and new routes of administration have emerged. If your post doesn't post, message a mod.SPRAY DELIVERY AS A NEWROUTE OF ADMINISTRATION Show us your work! Be proud of what you do, showing off your work could easily influence and inspire others! Be warned: pics are fine, but if it's too "spammy" your post will be removed. Share knowledge! Every screen printer does things a little differently share your techniques However, there's nothing wrong with general discussion.Īny links to videos, articles, websites, et. Hey I'm new to this, what type of ink do you guys suggest I start with and what are the differences in types of inks? Please refrain from posts that ask across-the-board questions. No matter what your skill level, whether you are a beginner who can't register a single image to a blank sheet of paper or a print god who yawns and lays down a four-color halftone perfectly with no hinge clamps or registration marks, there are ALWAYS questions. Visit the fine-art screen printing sub-reddit: /r/serigraphy We welcome most posts, typically: questions, interesting links, tips&tricks, etc. This is a subreddit specifically devoted to the art and crafts of serigraphy(screen printing).
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